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Observation 157

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Species Saccharomyces cerevisiae
Strain DBY746
Lifespan
Reference Lifespan
Lifespan Change 10%
Lifespan Measure
Lifespan Effect increased
Significance significant
Citation Fabrizio P, Liou LL, Moy VN, Diaspro A, Valentine JS, Gralla EB, Longo VD. (2003). SOD2 functions downstream of Sch9 to extend longevity in yeast.. Genetics 163: 35-46. [pubmed]
Details

Overexpression of CTT1 in combination with overexpression of SOD1 increases stationary phase survival by about 10%.

Other phenotypes: Overexpression of CTT1 alone slightly shortens stationary phase survival [pubmed].

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
CTT1 over-expression 852979 View
sod1 over-expression