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Observation 15

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Species Saccharomyces cerevisiae
Strain PSY316
Mating Type matalpha
Temperature 30
Lifespan 20.9 divisions
Reference Lifespan 22 divisions
Lifespan Change -5%
Lifespan Measure mean
Lifespan Effect decreased
Significance not significant
Citation Park PU, Defossez PA, Guarente L. (1999). Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae.. Mol. Cell. Biol. 19: 3848-56. [pubmed]

Deletion of RAD1 has no effect on life span.

Other phenotypes: Sensitive to UV-induced DNA damage [pubmed].

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
RAD1 deletion / null 856085 View