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Observation 140

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Species Drosophila melanogaster
Strain PdL x rtTA; Oregon-R x rtTA
Lifespan
Reference Lifespan
Lifespan Change
Lifespan Measure
Lifespan Effect increased
Significance significant
Citation Landis GN, Bhole D, Tower J. (2003). A search for doxycycline-dependent mutations that increase Drosophila melanogaster life span identifies the VhaSFD, Sugar baby, . Genome Biol. [pubmed]
Details

Overexpression of VhaSFD from a doxycycline-inducible promoter results in a 5-10% increase in mean life-span.

Other phenotypes: VhaSFD is involved in the acidificiation and energization of organelles.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
VhaSFD over-expression 34997 View