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Observation 14

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Species Caenorhabditis elegans
Strain N2
Sex hermaphrodite
Temperature 16
Lifespan 28 days
Reference Lifespan 21 days
Lifespan Change 33.33%
Lifespan Measure mean
Lifespan Effect increased
Significance significant
Citation Ishii N, Suzuki N, Hartman PS, Suzuki K. (1994). The effects of temperature on the longevity of a radiation-sensitive mutant rad-8 of the nematode Caenorhabditis elegans.. 49: B117-20. [pubmed]

Mutation of rad-8 increases life span by approximately 30%.

Other phenotypes: rad-8 mutants are hypersensitive to UV radiation, but not X-rays or MMS [pubmed].

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
rad-8 non-null recessive