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Observation 13

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Species Saccharomyces cerevisiae
Strain PSY316
Mating Type matalpha
Temperature 30
Lifespan 22.6 divisions
Reference Lifespan 20.5 divisions
Lifespan Change 10.24%
Lifespan Measure mean
Lifespan Effect increased
Significance not significant
Citation Lin SJ, Defossez PA, Guarente L. (2000). Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae.. Science 289: 2126-8. [pubmed]
Details

Deletion of QPT1 has no effect on life span.

Other phenotypes: QPT1 is not required for life span extension by caloric restriction. Mutation of QPT1 is synthetically lethal with mutation of NPT1 [pubmed].

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
QPT1 deletion / null