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Observation 127

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Species Drosophila melanogaster
Strain
Lifespan
Reference Lifespan
Lifespan Change
Lifespan Measure
Lifespan Effect increased
Significance significant
Citation Aigaki T, Seong KH, Matsuo T. (2002). Longevity determination genes in Drosophila melanogaster. Mech. Ageing Dev. [pubmed]
Details

Overexpression of DPOSH in post-mitotic neurons results in a 14% increase in mean life-span at 25C.

Other phenotypes: Ectopic expression of DPOSH during development results in morphological abnormalities [pubmed].

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
DPOSH over-expression