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Observation 124

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Species Saccharomyces cerevisiae
Strain PSY316
Lifespan
Reference Lifespan
Lifespan Change
Lifespan Measure
Lifespan Effect none
Significance
Citation Kaeberlein M, Andalis AA, Fink GR, Guarente L. (2002). High osmolarity extends life span in Saccharomyces cerevisiae by a mechanism related to calorie restriction.. Mol. Cell. Biol. 22: 8056-66. [pubmed]
Details

Deletion of TPS2 has no effect on life-span and does not prevent life-span extension by high osmolarity.

Other phenotypes: TPS2 is required for trehalose biosynthesis in response to osmotic stress [pubmed].

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
TPS2 deletion / null 851646 View