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Observation 118

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Species Saccharomyces cerevisiae
Strain PSY316
Lifespan
Reference Lifespan
Lifespan Change
Lifespan Measure
Lifespan Effect none
Significance
Citation Lin SJ, Kaeberlein M, Andalis AA, Sturtz LA, Defossez PA, Culotta VC, Fink GR, Guarente L. (2002). Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration.. Nature 418: 344-8. [pubmed]
Details

Deletion of CYT1 has no effect on life-span, but prevents life-span extension by overexpression of HAP4.

Other phenotypes: CYT1 is required for respiration in yeast.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
CYT1 deletion / null 854231 View