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Observation 109

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Species Saccharomyces cerevisiae
Strain YPK9
Lifespan
Reference Lifespan
Lifespan Change
Lifespan Measure
Lifespan Effect none
Significance
Citation Kirchman PA, Kim S, Lai CY, Jazwinski SM. (1999). Interorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae.. Genetics 152: 179-90. [pubmed]
Details

. Overexpression of CIT2 has no effect on life-span.

Other phenotypes: Deletion of CIT2 has no effect on life-span [pubmed]. CIT2 is not required for the strain specific life-span extension in petite cells. Overexpression of CIT2 has no effect on life-span [pubmed]. CIT2 is transcribed up to 30-fold higher in petite cells relative to grande cells [pubmed].

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
CIT2 over-expression 850361 View