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Observation 102

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Species Caenorhabditis elegans
Strain Bristol N2
Sex hermaphrodite
Temperature 20
Lifespan 21 days
Reference Lifespan 19.3 days
Lifespan Change 8.81%
Lifespan Measure mean
Lifespan Effect increased
Significance not significant
Citation Arantes-Oliveira N, Apfeld J, Dillin A, Kenyon C. (2002). Regulation of life-span by germ-line stem cells in Caenorhabditis elegans.. Science 295: 502-5. [pubmed]

Mutation of daz-1 has no effect on life span.

Other phenotypes: daz-1 mutants are sterile and have a gonad that contains small nuclei and no oocytes [pubmed]. Sperm production is normal. Oocyte precursors arrest at meiotic prophase and undergo apoptosis.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
daz-1 non-null recessive 173931 View