Sageweb.org > Tools

Observation 1000

Export: CSV XML YAML
Related Observations
User Comments

Please login to leave comments.

Species Caenorhabditis elegans
Strain N2
Sex hermaphrodite
Temperature 20
Lifespan 24.4 days
Reference Lifespan 24.4 days
Lifespan Change
Lifespan Measure mean
Lifespan Effect none
Significance
Citation Mehta R, Steinkraus KA, Sutphin GL, Ramos FJ, Shamieh LS, Huh A, Davis C, Chandler-Brown D, Kaeberlein M. (2009). Proteasomal regulation of the hypoxic response modulates aging in C. elegans. Science 324: 1196-8. [pubmed]
Details
RNAi knock-down of hif-1 had no significant effect on life span in the RNAi sensitive rrf-3(pk1426) background.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
hif-1 RNAi knockdown
rrf-3 pk1426 loss of function